Inter-filament co-operativity is crucial for regulating muscle contraction
نویسندگان
چکیده
منابع مشابه
Co-operativity in Spoken Dialogue 1 Running head: CO-OPERATIVITY IN SPOKEN DIALOGUE Co-operativity in Human-Machine and Human-Human Spoken Dialogue
The paper presents principles of dialogue co-operativity derived from a corpus of task-oriented spoken human-machine dialogue. The corpus was recorded during the design of a dialogue model for a spoken language dialogue system. Analysis of the corpus produced a set of dialogue design principles intended to prevent users from having to initiate clarification and repair meta-communication which t...
متن کاملIs titin a 'winding filament'? A new twist on muscle contraction.
Recent studies have demonstrated a role for the elastic protein titin in active muscle, but the mechanisms by which titin plays this role remain to be elucidated. In active muscle, Ca(2+)-binding has been shown to increase titin stiffness, but the observed increase is too small to explain the increased stiffness of parallel elastic elements upon muscle activation. We propose a 'winding filament...
متن کاملRole of Active Contraction and Tropomodulins in Regulating Actin Filament Length and Sarcomere Structure in Developing Zebrafish Skeletal Muscle
Whilst it is recognized that contraction plays an important part in maintaining the structure and function of mature skeletal muscle, its role during development remains undefined. In this study the role of movement in skeletal muscle maturation was investigated in intact zebrafish embryos using a combination of genetic and pharmacological approaches. An immotile mutant line (cacnb1 (ts25) ) wh...
متن کاملNegative co-operativity in the EGF receptor.
Scatchard analyses of the binding of EGF (epidermal growth factor) to its receptor (EGFR) yield concave up Scatchard plots, indicative of some type of heterogenity in ligand-binding affinity. This was typically interpreted as being due to the presence of two independent binding sites: one of high affinity representing ≤10% of the receptor population, and one of low affinity making up the bulk o...
متن کاملThe need for muscle co-contraction prior to a landing.
In landings from a flight phase the mass centre of an athlete experiences rapid decelerations. This study investigated the extent to which co-contraction is beneficial or necessary in drop landings, using both experimental data and computer simulations. High speed video and force recordings were made of an elite martial artist performing drop landings onto a force plate from heights of 1.2, 1.5...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2017
ISSN: 0022-3751
DOI: 10.1113/jp275414